IL16 anticorps
Aperçu rapide pour IL16 anticorps (ABIN114536)
Antigène
Voir toutes IL16 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- Reactive with natural and recombinant Human IL-16. This monoclonal antibody exhibits no detectable cross-reacting with Human Albumin Serum, Bovine Albumin Serum and other Human cytokines or growth factors tested such as IL-1beta, IL-8, IL-7 MCAF, TGF-beta1, EGF, bFGF, GM-CSF, M-CSF, TNF-alpha.
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Purification
- Protein G affinity purified
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Immunogène
- Purified recombinant human IL-16
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Isotype
- IgG1
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Indications d'application
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ELISA: This antibody can be used as a capture antibody in sandwich ELISA applications forhuman IL-16 detection in combination with a monoclonal tracer/detection antibody. Suggested Capture Coating Dose: 0.3g/well, Substrate: TMB. If the above suggested conditions are followed, approximately 20pg/mL of IL-16 inserum/plasma or 15 pg/mL of IL-16 in cell medium/urine can be detected with an assayrange of 0-1000 pg/mL
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Reconstitution
- Restore with Double distillated water is recommended and to adjust the final concentration to 1.0 mg/mL
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Buffer
- 0.01 M PBS, pH 7.2
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Stock
- 4 °C
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Stockage commentaire
- Store the antibody at 2 - 8 °C. Do not freeze.
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- IL16 (Interleukin 16 (IL16))
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Autre désignation
- Interleukin-16 / IL16
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Sujet
- IL16 is a proinflammatory cytokine that is chemotactic for CD4+ T lymphocytes, monocytes, and eosinophils. IL16 is synthesized as a precursor molecule (pro IL16) of approximately 68 kDa and 631 amino acid residues lacking a signal peptide. The sequence and structure of IL16 is conserved across species. In addition to inducing chemotaxis, IL16 upregulates the IL2 receptor and upregulates HLADR expression. It also inhibits T cell receptor (TCR)/CD3 dependent activation, and suppresses HIV1 replication in vitro. Sources of IL16 include epithelial cells, mast cells, T lymphocytes (CD4+ and CD8+), macrophages, synovial fibroblasts, and eosinophils.Synonyms: IL-16, LCF, Lymphocyte chemoattractant factor
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ID gène
- 3603
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NCBI Accession
- NP_001165599
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UniProt
- Q14005
Antigène
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